{"modelId":"v24_source_feature_integration","modelTrainingStatus":"trained_successfully","researchTriageStatus":"ready_for_governed_research_triage","clinicalReadinessStatus":"blocked_pending_clinical_validation","diseaseDetectionStatus":"not_ready_for_clinical_disease_detection","clinicalUseStatus":"prohibited","canClaimDiseaseDetection":false,"blockingGateCount":7,"candidateThreshold":0.71,"readinessSummary":"v24 is trained successfully and ready for governed research triage, but patient-level validation missing or incomplete; prospective validation readiness exists through Pass111 but real prospective evidence is not complete. Therefore it is not ready for clinical disease detection, diagnosis, treatment decisions, or patient-specific interpretation.","blockingGates":["disease_specific_endpoint_definition","retrospective_patient_level_validation","prospective_multisite_validation","subgroup_bias_and_calibration","clinical_risk_management_qms","regulatory_pathway_review","postmarket_monitoring_pccp"],"nextActions":["Acquire an IRB/DUA-appropriate deidentified patient-level clinical cohort with clinician-adjudicated disease/phenotype endpoints.","Lock the intended-use statement, disease-specific endpoint, inclusion/exclusion criteria, and analysis plan before touching patient-level validation data.","Run retrospective patient-level validation of the frozen v24 scorer at threshold 0.71, including sensitivity, specificity, PPV, NPV, calibration, and decision-curve analysis.","Run subgroup bias and calibration checks by site, assay, ancestry, age, sex, and phenotype severity before any clinical workflow claim.","Pre-register and run a prospective multisite validation workflow before any disease-detection, diagnosis, or treatment-support use.","Use the Pass111 protocol and event template only after Pass110 passes on real deidentified cohort evidence.","Prepare clinical risk management, quality-system traceability, monitoring, rollback, and AI change-control documentation before regulatory review."],"readinessArtifactPath":"/repo/artifacts/downloads/training/pass100_clinical_translation_readiness_v1.json"}